- Steve Shak, Chris Carrieri, Chris Gbandi, Alecko Eskandarian, Freddy Adu, Nik Besagno, Marvell Wynne, Maurice Edu, Chance Myers, Steve Zakuani
- Nick Garcia, Ali Curtis, Taylor Twellman, Ricardo Clark, Chad Marshall, Brad Guzan, Mehdi Ballouchy, Bakary Soumare, Brek Shea, Sam Cronin
- Adin Brown, Mark Lisi, Brad Davis, Nate Jaqua, Joseph Ngwenya, Chad Barrett, Jason Garey, Michael Harrington, Anthony Beltran, Omar Gonzalez
- Carlos Bocanegra, Ryan Nelsen, Justin Mapp, Mike Magee, Matt Taylor, Danny O’Rourke, Yura Movsisyan, Chris Seitz, Sean Franklin, O’Brian White
- Aleksey Korol, Joselito Vaca, Kelly Gray, David Strokes, Ryan Cochrane, Ugo Ihemelu, Sacha Kljestan, Wells Thompson, Ciaran O’Brien, Peri Marosevic
- Danny Califf, Craig Demmin, Luchi Gonzalez, Todd Dunivant, Ramon Nunez, Drew Moor, Dax McCarty, Nica Colaluca, Andy Iro, Rodney Wallace
- Wes Hart, Ryan Suarez, Mansour Nidaye, Diego Walsh, Clearance Goodson, Hunter Freeman, Justin Moose, John Cunliffe, Patrick Nyarko, Chris Pontius
- Travis Mulraine, Santino Quaranta, Kyle Martino, Guillermo Gonzalez, Clint Dempsey, Troy Roberts, Patrick Ianni, Jerson Monteiro, Josh Lambo, Matt Besler
- John Wilson, Brian Mullan, Carl Bussey, Pat Nooan, Scott Buete, Michael Parkhurst, Kei Kamara, Anthony Wallace, Julius James, Michael Lahoud
- Alan Woods, Duncan Oughton, Billy Sleeth, Shavar Thomas, Steve Cronin, Jack Stewart, Calen Carr, Andrew Boyens, Pat Phelan, Kevin Alston
- Sasha Victorine, Isaias Bardales, Daouda Kante, Brian Carroll, Leonard Griffin, Scott Sealy, Leonardo de Oliviera, Bryan Arguez, Roger Espinoza, Jeremy Hall
- Bobby Convey, Jose Burciaga, Lee Morrison, Eddie Gaven, Chris Wingert, Tim Ward, Nathan Sturgis, Amaechi Igwe, Dominic Cervi, Jean Alexandre
- Stephen Armstrong, Rodrigo Faria, Hemir Neibles, Arturo Alvarez, Josh Gardner, Jamie Watson, Jed Zayner, John Michael Hayden, Rob Valentino, Stefan Frei
- Rusty Pierce, Devin Barclay, Shalrie Joseph, Doug Warren, Ned Grabavoy, Christian Jimenez, Jeff Curtin, Abdus Ibrahim, David Horst, George John
- Peter Byaruhanga, Bryan Namoff, Jordan Stone, Jason Thompson, Adolfo Gregorio, Michael Enfield, Justin Moore, Brad Evans, Shea Salinas, Ryan Maxwell
- Justin Evans, Brian Ching, Danny Jackson, Scot Thompson, Adrian Cann, Ryan Pore, Lance Watson, Robbie Findley, Eric Brunner, Evan Brown
Rookie of the Year selections bolded
